Alberto Guerron1, Suzanne Giasson1,2 1) Department of Chemistry, Université de Montréal, C. P. 6128, Succursale Centre-ville, Montreal, QC H3C 3J7, Canada 2) Faculty of Pharmacy, Université de Montréal, C. P. 6128, Succursale Centre-ville, Montreal, QC H3C 3J7, Canada Stimuli-responsive polymer coatings can be used as functional elements in nanotechnologies such as valves in microfluidic devices, as membranes in biomedical engineering, as substrates for culture of biological tissues or substrates of low friction. However, such coatings usually suffer from major shortcomings such as lack of selectivity and poor environmental stability. The talk will present a new generation of multi-responsive hierarchical and hybrid polymer coatings aiming to overcome some of these limitations. A hierarchical polymer coating, consisting of two-dimensional thermo-responsive microgel arrays and surface-functionalized with non-responsive or pH-responsive polymers, was developed to tune independently its surface chemistry and the swelling behavior using different stimuli. The responsiveness of the hierarchical coatings was investigated using the Surface Forces Apparatus allowing adhesion, friction and layer thickness to be accurately determined under different stimuli. The talk will report results showing how the characteristic dimensions (i.e. layer thickness) can indeed be controlled without affecting the surface properties (i.e. adhesion) of the functionalized microgel arrays.